Dr. William Heberden, a London physician, described the first cases of Henoch- Schönlein purpura (HSP) in In describing HSP, Heberden wrote of a. Henoch-Schönlein purpura (HSP) affects the blood vessels and causes a spotty rash. It’s not usually serious, but can sometimes lead to kidney problems. Henoch–Schönlein purpura (HSP) is a disease of the skin, mucous membranes, and sometimes other organs that most commonly affects children. In the skin.

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It affects both sexes equally. Treatment may be indicated on the basis of the appearance of the biopsy sample; various treatments may be used, ranging from steroids by mouth to a combination of intravenous methylprednisolone steroidcyclophosphamide and dipyridamole followed by prednisone. Beta blockers, calcium channel blockers, and other blood pressure medications may also be needed.

Supportive care may involve a short course of prednisone or an NSAID, such as naprosyn or ibuprofen, if the kidneys are not involved. Palpable purpura can appear in many different patterns. It’s not usually serious, but can sometimes lead to kidney problems.

The English physician William Heberden — and the dermatologist Robert Willan — had already described henkch disease in andrespectively, but the name Heberden—Willan disease has fallen into disuse. In the skin, the disease causes palpable purpura small, raised areas of bleeding underneath the skinoften with joint pain and abdominal pain.

This may occur in the first week or so of the illness, but there may be a delay of weeks or months before it appears.

Adalha kidney involvement, there may be a loss of small amounts of blood and protein in the urine hematuria and proteinuriabut schknlein usually goes unnoticed; in a small proportion of cases, the kidney involvement proceeds to chronic kidney disease.


Henoch-Schönlein purpura (HSP)

Important How to do the glass test Press the side of a clear glass firmly against the skin. Despite this association, no single microorganism or environmental genoch has been confirmed as an important cause of HSP. Biopsy of the kidney may be performed both to establish the diagnosis or to assess the severity of already suspected kidney disease.

I have some feedback on: It is believed that similar abnormalities may underlie HSP. In two-thirds of the cases, the disease follows an upper respiratory tract infection, with onset an average of ten days after the start of respiratory symptoms.

About Paediatric Society of New Zealand.

Henoch-Schonlein purpura – Symptoms, diagnosis and treatment | BMJ Best Practice

Swelling around the ankle and foot. These are not repairable and are associated with some loss of function- this is why recurrent bouts of HSP can lead to progressive kidney damage and your doctors will monitor your kidney function, presence and quantity of blood and protein in the urine. Bowel symptoms may be severe and can present as a severe appendicitis. Your doctor will want to check urine samples and blood pressure several times after the HSP goes away to check for kidney problems.

So, if your adalwh has a fever with this rash, call an ambulance. People with HSP that is causing high blood pressure may need to take medications that—when taken as prescribed by their health care provider—lower their blood pressure and can also significantly slow the progression of kidney disease.

The condition usually improves on its own.


No specific treatment for HSP exists. The majority of the serines and the threonines have elaborate sugar chains, connected through oxygen atoms O-glycosylation. Though the rash affects all people with HSP, pain in the joints or abdomen precedes the rash adala about one-third of cases by as many as 14 days. What are the causes of HSP? This may be done at home, at your GP surgery, or in hospital.

Evidence of worsening kidney damage would normally prompt a hencoh biopsy. There is no good evidence that treating children who have HSP with antiplatelet agent prevents persistent kidney disease.

About Vasculitis

With this condition, a section of the bowel folds into itself like a telescope, causing the bowel to become blocked. Cases of HSP may occur anytime throughout the year, but some studies purpuraa found that fewer cases occur during the summer months. Allergic contact dermatitis Mantoux test. Diabetes mellitus type 1 Hashimoto’s thyroiditis Multiple sclerosis Coeliac disease Giant-cell arteritis Postorgasmic illness syndrome Reactive arthritis.

As with IgA nephropathyserum levels of IgA are high in HSP and there are identical findings on renal biopsy; however, IgA nephropathy has a predilection for young adults while HSP is more predominant among children. Usually the disease stops re-occurring as patients get older. From Wikipedia, the free encyclopedia.

If your child has Henoch-Schonlein purpura, you may first notice a rash. It usually appears on the buttocks, on the legs and around the elbows.